INBDE practice

INBDE General & Oral Pathology practice questions

18 board-style questions on general & oral pathology, written to the INBDE blueprint. Pick an answer to see whether you got it and why. The first 10 are open to everyone.

Inflammation, healing, and cellular adaptationOdontogenic cysts and tumorsPremalignant and malignant oral lesionsWhite and red mucosal lesions differentialSalivary gland pathologySystemic diseases with oral manifestationsRadiographic differential of jaw lesions
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10 free questions, 8 with a free account
Question 1

A 45-year-old male presents with a painless, slow-growing swelling in the posterior mandible. Radiographs reveal a multilocular 'soap-bubble' radiolucency and significant root resorption of the adjacent molars. What is the most likely diagnosis?

Question 2

A 22-year-old female presents for a routine check-up. An incidental finding on the panoramic radiograph shows a well-defined, unilocular radiolucency extending from the distal of the mandibular third molar into the ramus. A biopsy shows a cyst lined by a uniform layer of parakeratinized stratified squamous epithelium with a corrugated surface. What is the most critical clinical consideration for this lesion?

Question 3

A 62-year-old male patient with a 40-pack-year smoking history presents with an asymptomatic 2x1 cm red, velvety patch on the floor of the mouth. The lesion does not wipe off. What is the most appropriate next step and the suspected malignant potential?

Question 4

A patient presents with a non-vital maxillary lateral incisor associated with a well-circumscribed 1 cm periapical radiolucency. Histologically, the lesion consists of a connective tissue wall and a lumen lined by stratified squamous epithelium. What distinguishes this lesion from a periapical granuloma?

Question 5

A 55-year-old female presents with multiple painful oral ulcers and blisters. She reports that a blister recently formed on her buccal mucosa after the dentist rubbed it with a cotton roll (positive Nikolsky sign). Histopathology shows intraepithelial clefting above the basal layer (acantholysis). What is the target of the autoantibodies in this condition?

Question 6

A 35-year-old patient presents with white, lacy, thread-like lines (Wickham striae) bilaterally on the buccal mucosa. The patient is asymptomatic. What is the most likely diagnosis, and what is the characteristic histological feature?

Question 7

A patient presents with a firm, slow-growing, painless mass in the parotid gland that has been present for several years. Histology shows a mixture of glandular epithelium and mesenchymal-like elements (chondroid and myxoid tissue). What is the most likely diagnosis?

Question 8

A 10-year-old child presents with a soft, fluctuant, bluish swelling on the lower lip. The mother states the lesion increases and decreases in size and appeared after the child bit their lip. What is the underlying pathogenesis?

Question 9

A 50-year-old female with a history of dry eyes and xerostomia presents for a dental exam. She has a high caries rate and bilateral parotid enlargement. Laboratory tests reveal positive SS-A and SS-B antibodies. This patient has a significantly increased risk for which of the following?

Question 10

A 30-year-old patient presents with a well-defined radiolucency surrounding the crown of an unerupted mandibular third molar. The radiolucency is attached to the tooth at the cementoenamel junction (CEJ). What is the most likely diagnosis?

The first 10 are free. 8 more below.

A free account unlocks the remaining 8 questions and their explanations, and lets you add the full INBDE path with spaced review that brings back the ones you miss.

Question 11 Locked

A 19-year-old male presents with fatigue, pale mucosa, and significant gingival enlargement that bleeds easily upon probing. He has no history of taking anti-seizure or calcium channel blocking medications. What systemic condition should be strongly suspected?

Question 12 Locked

Which of the following sites in the oral cavity has the highest risk for the development of Squamous Cell Carcinoma (SCC)?

Question 13 Locked

A 28-year-old patient presents with 'cobblestone' appearance of the buccal mucosa and deep linear ulcerations in the vestibule. The patient also reports chronic abdominal pain and diarrhea. Which condition is most likely?

Question 14 Locked

A 75-year-old 'snuff' dipper presents with a large, white, exophytic, warty mass on the mandibular alveolar ridge. The lesion is slow-growing and has a 'pebbly' surface. Histology shows well-differentiated squamous epithelium with minimal atypia and 'pushing' rete pegs. What is the diagnosis?

Question 15 Locked

A patient's panoramic radiograph reveals multiple osteomas of the jaws and several impacted supernumerary teeth. The dentist refers the patient to a gastroenterologist for a colonoscopy. What is the rationale for this referral?

Question 16 Locked

A 40-year-old HIV-positive patient presents with non-wipeable, white, vertical corrugated lines on the lateral borders of the tongue. The lesion is asymptomatic. What is the causative agent of this condition?

Question 17 Locked

A radiograph shows a well-defined, multilocular radiolucency in the mandible that displaces teeth and appears to 'step between' the roots. Histological exam shows loose, spindle-shaped cells in a highly myxoid, 'jelly-like' stroma with very little collagen. What is the diagnosis?

Question 18 Locked

An 80-year-old patient presents with a redundant fold of fibrous tissue in the maxillary vestibule where the flange of their poorly fitting denture sits. The lesion is firm and not painful. This is an example of which cellular adaptation or process?

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